You can add appointments to your routes using Mapsly. To do that you need to simply enable the Add from calendar checkbox in the Route pane.

Once you do that, all of the appointments for that day will be added to the route. You can also plan future routes by changing the departure date and time using arrows:

Note, that your meeting must be linked to a record that is lead/contact/account or any other entity that you are using in your CRM. It should also have a valid address, otherwise the appointment will not be added to the route.